Saccadometry as an Outcome Assessment in Headache and Cognition

Presentation: A 39 year-old, male, medical physician presented with headaches, difficulty concentrating, difficulty remembering, fatigue, feeling “in a fog,” and increased emotionality. Each of these were 6/6 on subjective symptom assessment. The patient was evaluated diagnostically by the use of saccadometry. Saccadometry is the evaluation of saccadic eye movements using infrared laser technology. Saccadometry quantifies the latency, position, velocity, and amplitude of saccade. Each diagnostic session consisted of 50 saccades to the left and 50 to the right.

Methods: The patient was treated over a 4 day span that included three treatment sessions per day that lasted an hour. The treatment consisted of gaze stability exercises, non-invasive neuromodulation of the tongue and face, breathing exercises, and active figure-of-eight limb movements.

Results: The peak velocity means before treatment was 681°/s to the left and 781°/s to the right. The amplitude mean of rightward saccades was 17.0°. After treatment, the peak velocity means were 991°/s to the left and 1043°/s to the right (Z scores of 7.58 and 6.13, respectively). The amplitude mean of rightward saccades increased to 19.6°.

Conclusion: The saccadic velocity waveform should be uniform without transient acceleration or deceleration sequences. The rapid improvement velocity waveforms and phase plots in this patient demonstrate a significant outcome. The patient experienced reduced severity of symptoms after treatment. This suggests that an intensive neurological treatment approach and the diagnostic data provided by saccadometry are important clinical aspects in neurological rehabilitation. It also suggests that saccades may be a biomarker representing neurological integrity in clinical assessment.

Antonucci MM, Sass BJ, Sass CM(2015). UTILIZATION OF SACCADOMETRY IN AN INTENSIVE MULTIMODAL NEUROLOGICAL APPROACH TO A PATIENT WITH HEADACHES AND COGNITIVE IMPAIRMENTS. Front. Neurol. Conference Abstract: International Symposium on Clinical Neuroscience: TBI and Neurodegeneration. doi:10.3389/conf.fneur.2015.58.00079

#saccade #cognition #headache #posterpresentation #abstract

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